Laboratoire de Physique et Chimie des Nano-objets

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Accueil du site > LPCNO > Équipes > Réceptologie et Ciblage Thérapeutique en Cancérologie > Publications

Réceptologie et Ciblage Thérapeutique en Cancérologie. : Publication de l'équipe

Publications classées par type / année

Liste des publications / Publications List

Année / Year 2016

Influence on Cell Death of High Frequency Motion of Magnetic Nanoparticles during Intra-lysosomal Magnetic Hyperthermia Experiments
N. Hallali, V. Gigoux, P. Clerc, D. Fourmy and J. Carrey
Appl. Phys. Lett. 109, 032402 (2016)

Année / Year 2015

GPCR structure, function, drug discovery and crystallography : report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014
Heifetz, A., Schertler, G.F., Seifert, R., Tate, C.G., Sexton, P.M., Gurevich, V.V., Fourmy, D., Cherezov, V., Marshall, F.H., Storer, R.I., Moraes, I., Tikhonova, I.G., Tautermann, C.S., Hunt, P., Ceska, T., Hodgson, S., Bodkin, M.J., Singh, S., Law, R.J. and Biggin
Naunyn Schmiedebergs Arch Pharmacol 388, 883-903.

Internalization and desensitization of the human glucose-dependent-insulinotropic receptor is affected by N-terminal acetylation of the agonist.
Ismail, S., Dubois-Vedrenne, I., Laval, M., Tikhonova, I.G., D’Angelo, R., Sanchez, C., Clerc, P., Gherardi, M.J., Gigoux, V., Magnan, R. and Fourmy,
Mol Cell Endocrinol 414, 202-15.

Pancreatic preneoplastic lesions plasma signatures and biomarkers based on proteome profiling of mouse models.
Ligat, L., Saint-Laurent, N., El-Mrani, A., Gigoux, V., Al Saati, T., Tomasini, R., Nigri, J., Dejean, S., Pont, F., Baer, R., Guillermet-Guibert, J., Cordelier, P., Lopez, F. and Dufresne,
Br J Cancer 113, 1590-8.

Gastrin-stimulated Galpha13 Activation of Rgnef Protein (ArhGEF28) in DLD-1 Colon Carcinoma Cells.
Masia-Balague, M., Izquierdo, I., Garrido, G., Cordomi, A., Perez-Benito, L., Miller, N.L., Schlaepfer, D.D., Gigoux, V. and Aragay, A.M. (2015)
J Biol Chem 290, 15197-209.

Real-Time Analysis of Magnetic Hyperthermia Experiments on Living Cells under a Confocal Microscope.
Connord, V., Clerc, P., Hallali, N., El Hajj Diab, D., Fourmy, D., Gigoux, V. and Carrey, J.
Small 11, 2437-45.

Functional elements of the gastric inhibitory polypeptide receptor : Comparison between secretin- and rhodopsin-like G protein-coupled receptors.
Cordomi, A., Ismail, S., Matsoukas, M.T., Escrieut, C., Gherardi, M.J., Pardo, L. and Fourmy, D.
Biochem Pharmacol 96, 237-46.

Targeted nanoscale magnetic hyperthermia : challenges and potentials of peptide-based targeting.
Fourmy, D., Carrey, J. and Gigoux, V.
Nanomedicine (Lond) 10, 893-6.

Année / Year 2014

The glucose-dependent insulinotropic polypeptide receptor : a novel target for neuroendocrine tumor imaging-first preclinical studies.
Gourni, E., Waser, B., Clerc, P., Fourmy, D., Reubi, J.C. and Maecke, H.R.
J Nucl Med 55, 976-82.

The E3 ubiquitin ligase thyroid hormone receptor-interacting protein 12 targets pancreas transcription factor 1a for proteasomal degradation.
Hanoun, N., Fritsch, S., Gayet, O., Gigoux, V., Cordelier, P., Dusetti, N., Torrisani, J. and Dufresne, M.
J Biol Chem 289, 35593-604.

Transdifferentiation of pancreatic alpha-cells into insulin-secreting cells : From experimental models to underlying mechanisms.
Lu, J., Jaafer, R., Bonnavion, R., Bertolino, P. and Zhang, C.X.
World J Diabetes 5, 847-53.

Targeting a G-protein-coupled receptor overexpressed in endocrine tumors by magnetic nanoparticles to induce cell death.
Sanchez, C., El Hajj Diab, D., Connord, V., Clerc, P., Meunier, E., Pipy, B., Payre, B., Tan, R.P., Gougeon, M., Carrey, J., Gigoux, V. and Fourmy, D.
ACS Nano 8, 1350-63.

Année / Year 2013

Sulfur-containing amino acids in 7TMRs : molecular gears for pharmacology and function.
Cordomi, A., Gomez-Tamayo, J.C., Gigoux, V. and Fourmy, D.
Trends Pharmacol Sci 34, 320-31.

Acting on Hormone Receptors with Minimal Side Effect on Cell Proliferation : A Timely Challenge Illustrated with GLP-1R and GPER.
Gigoux, V. and Fourmy, D.
Front Endocrinol (Lausanne) 4, 50.

Distinct CCK-2 receptor conformations associated with beta-arrestin-2 recruitment or phospholipase-C activation revealed by a biased antagonist.
Magnan, R., Escrieut, C., Gigoux, V., De, K., Clerc, P., Niu, F., Azema, J., Masri, B., Cordomi, A., Baltas, M., Tikhonova, I.G. and Fourmy, D.
J Am Chem Soc 135, 2560-73.

Année / Year 2012

A switch of G protein-coupled receptor binding preference from phosphoinositide 3-kinase (PI3K)-p85 to filamin A negatively controls the PI3K pathway.
Najib, S., Saint-Laurent, N., Esteve, J.P., Schulz, S., Boutet-Robinet, E., Fourmy, D., Lattig, J., Mollereau, C., Pyronnet, S., Susini, C. and Bousquet, C.
Mol Cell Biol 32, 1004-16.

Characterization of a novel five-transmembrane domain cholecystokinin-2 receptor splice variant identified in human tumors.
Sanchez, C., Escrieut, C., Clerc, P., Gigoux, V., Waser, B., Reubi, J.C. and Fourmy, D.
Mol Cell Endocrinol 349, 170-9.

Année / Year 2011

Id3 modulates cellular localization of bHLH Ptf1-p48 protein.
Dufresne, M., Clerc, P., Dieng, M., Edir, A., Couvelard, A., Delisle, M.B., Fourmy, D. and Gigoux, V.
Int J Cancer 129, 295-306.

Gastrin in gastrointestinal diseases.
Fourmy, D., Gigoux, V. and Reubi, J.C.
Gastroenterology 141, 814-818 e1-3.

Regulation of membrane cholecystokinin-2 receptor by agonists enables classification of partial agonists as biased agonists.
Magnan, R., Masri, B., Escrieut, C., Foucaud, M., Cordelier, P. and Fourmy, D.
J Biol Chem 286, 6707-19.

New anthranilic acid based antagonists with high affinity and selectivity for the human cholecystokinin receptor 1 (hCCK1-R).
Pavan, M.V., Lassiani, L., Berti, F., Stefancich, G., Ciogli, A., Gasparrini, F., Mennuni, L., Ferrari, F., Escrieut, C., Marco, E., Makovec, F., Fourmy, D. and Varnavas, A.
J Med Chem 54, 5769-85.

TP53INP1 decreases pancreatic cancer cell migration by regulating SPARC expression.
Seux, M., Peuget, S., Montero, M.P., Siret, C., Rigot, V., Clerc, P., Gigoux, V., Pellegrino, E., Pouyet, L., N’Guessan, P., Garcia, S., Dufresne, M., Iovanna, J.L., Carrier, A., Andre, F. and Dusetti, N.J.
Oncogene 30, 3049-61.

Année / Year 2010

Alpha cell-specific Men1 ablation triggers the transdifferentiation of glucagon-expressing cells and insulinoma development.
Lu, J., Herrera, P.L., Carreira, C., Bonnavion, R., Seigne, C., Calender, A., Bertolino, P. and Zhang, C.X.
Gastroenterology 138, 1954-65.

The family of G protein-coupled receptors : an example of membrane proteins.
Tikhonova, I.G. and Fourmy, D.
Methods Mol Biol 654, 441-54.

Identification of determinants of glucose-dependent insulinotropic polypeptide receptor that interact with N-terminal biologically active region of the natural ligand.
Yaqub, T., Tikhonova, I.G., Lattig, J., Magnan, R., Laval, M., Escrieut, C., Boulegue, C., Hewage, C. and Fourmy, D.
Mol Pharmacol 77, 547-58.

Thèses / Thesis

Liste des brevets / Patents List