Laboratoire de Physique et Chimie des Nano-objets

Institut National des Sciences Appliquées
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Magnetic nanoparticles heat up at the LPCNO

A. Meffre et al., Nano Letters 12, 4722 (2012 )

Magnetic hyperthermia consists in raising the temperature of a tumour using magnetic nanoparticles and high-frequency magnetic fields. Two teams of the laboratory have been working for several years to maximize the heating properties of magnetic nanoparticles. Recently, they have shown the potential of iron carbide nanoparticles for this application. Indeed, they reported a tunable organometallic synthesis of monodisperse iron carbide (MM1) and core/shell iron/iron carbide (MM2) nanoparticles displaying a high magnetization and good air-stability. This process based on the decomposition of Fe(CO)5 on Fe(0) seeds allows the control of the amount of carbon diffused and therefore the tuning of nanoparticles magnetic anisotropy. This results in unprecedented hyperthermia properties at moderate magnetic fields, in the range of medical treatments.

Joint work of “Nanostructures and Organometallic Chemistry” and “Nanomagnetism” groups.

For more details, see A. Meffre and co-workers, Nano Letters 2012, 12, 4722−4728.

Schematic of the synthetic method used to produce the iron carbide nanoparticles, and corresponding transmission electron microscopy images.