Laboratoire de Physique et Chimie des Nano-objets

Institut National des Sciences Appliquées
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Home page > LPCNO > Seminars > 2013 > Porous (nano)materials. Properties and applications

Porous (nano)materials. Properties and applications

Date : 05/12/2013 à 14:30

Titre : Porous (nano)materials. Properties and applications

Intervenant : Luisa De Cola

Provenance : Institute de Science et d’Ingénierie Supramoléculaires (I.S.I.S.), Université de Strasbourg and KIT

Salle : Salle de séminaire

Résumé: In the group the synthesis and characterization of soft and hard porous structures is since few years one of the focus of our research. The talk will illustrate some of the recent results on microporous and mesoporous silica based nanoparticles. In particular examples using the crystalline allumino silicates, zeolite L, will be discussed since these materials can act as nanocontainers and due to their biocompatibility used for biomedical applications. The different functionalization of their surface will be discussed, in particular with the aim to show that the particles can be decorated with different functional groups including biocompatible molecules and are able to perfom drug and DNA or RNA delivery inside the cell [1]. The delivery can be probed by a kinetic analyses after the nanoparticles internalization. In particular using confocal fluorescent microscopy it is possible to follow the release of each single component as well as the positioning of the nanocontainers in real time and space. Such achievement allows us to study the fate of the different units and their release time. Also it will be shown how the molecules entrapped in the ordered channels can become active components. The alignment of electroactive molecules inside the narrow channels of a zeolite L, resulted in the formation of molecular wires. The molecular wire length is tunable between 30 and 100 nm and electrical measurements on the 1D assemblies were performed. Finally an ultra-high (> 2000%) room-temperature magnetoresistance was observed applying only a few mT [2]. Finally it will be discussed how the morphology of such nanocontainers can be important for the creation of patterned substrates on which different cells can preferentially adhere [3]. The growth and prolification of the cells can be selectively controlled only on small areas of the surfaces as well as promoted in a soft matrix sandwiched in between the rigid scaffolds [4].

[1] Z. Li, L. De Cola, C. Krampe, J. Hüve, J. Klingauf, G. Luppi, M. Tsotsalas, K. Riehemann Small, 2013, 9, 1809-1820. R. Corradini, L. De Cola et al unpublished results
[2] L. De Cola, W.G. van der Wiel et al. Science, 2013, 341, 257.
[3] J. El-Gindi, K. Benson, L. De Cola, H.-J. Galla, N.S. Kehr Angew. Chem. Int. Ed., 2012, 51, 3716-3720. _[4] O.Z. Fisher, B.L. Larson, P.S. Hill, D. Graupner, M.-T. Nguyen-Kim, N.S. Kehr, L. De Cola, R. Langer, D.G. Anderson Adv. Mat., 2012, 24, 3032-3036